The discovery of slimming capsules which made spending hours in a fitness center as well as adhering to a strict dieting program redundant to a certain extent, produced a rage in the marketplace. They ended up to be a blessing in disguise for the entire pharmaceutical industry, which in turn is present day earning of significant revenues with the purchase of these pills. It’s been estimated that more than 20 million of Americans consume diet drugs each year.
The History of Diet Pills
It was during the ten years of 1950s when science as well as medicine had been producing striking achievements that these products were first prescribed by the physicians to the individuals. The doctors prescribed amphetamines, a drug applied to the World War II to maintain soldiers alert and productive, for weight loss objective. One of the side effects of amphetamines was appetite suppression that led doctors in prescribing them as weight loss supplements. Before long numerous fat loss individuals had amphetamines led substance abuse issues as well as its prescription was inhibited.
It was in 1970s when wellness consciousness sprung up to its pinnacle as well as fitness became a global craze. Weight reduction became the title of the game and the pharmaceutical industry saw a sudden boom in the need for them. The first such drugs in this era were essentially amphetamines derivatives, normally known as “speed”. Afterwards, an assortment of fat reduction pills flooded the market.
Food as well as Drug Administration (FDA) approved the drug fenfluramine (Pondimin) in as early as 1973, which was followed by dexfenfluramine (Redux) in 1996. After that came the diet drug Phentermine, a sympathomimetic appetite suppressant, which was authorized by the FDA in 1997. Numerous medical professionals prescribed Phentermine in conjunction with fenfluramine. The combined prescription of each prescription drugs was aptly named fen phen.
The era of fen phen soon declined with accounts of heart valve disease resulting from the combined utilization of each drugs began to surface. The manufacturers withdrew dexfenfluramine as well as fenfluramine from the industry, therefore ending the rule of fen-phen.
The most used weight reduction drugs that are recommended in the US are sympathomimetic appetite suppressants like Phentermine. These medications impact the neurotransmitters in such a manner that causes a loss in appetite.
Other weightloss pills that received FDA approval are Orlistat (Xenical) and Sibutramine (Meridia), which received approval in 1999 and 2001 respectively. While Orlistat is a lipase inhibitor which inhibits the absorption of soluble fats into the human body, Sinutramine functions on mind through serotonin, Visit website norepinephrine and dopamine reuptake inhibition.